Fig. 1. Annexin V assay confirms late apoptosis as one of the mechanisms of 2155-14-induced cell death. Starurosporine was used at 1 µM, 2155-14 was used at 100 µM, and pan-caspase inhibitor Z-VAD-FMK was used at 10 µM. Cells treated with 2155-14 and 2155-14+pan-caspase inhibitor have similar distribution of cell populations suggesting lack of pan-caspase inhibitor activity on biological effects of 2155-14 application.